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NF449

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CAS:389142-38-5Formula:C41H24N6O29S88NaMW:1505.1Appearance:PaleredSolidPackagedunderinertgasPurity:95%byHPLC

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A potent Gsa-subunit-selective G-protein antagonist. Suppresses the rate of GTPS binding to Gsa-s-subunit (IC = 140 nM) but not to Gi1-subunit.

Product #	N-1207
CAS #	389142-38-5
Formula	C₄₁H₂₄N₆O₂₉S₈ ₈Na
MW	1505.1
Appearance	Pale red Solid Packaged under inert gas
Purity	95% by HPLC
Solubility	Soluble in Water
Storage Temp	+4°C
Use	A selective G-protein antagonist

MDL Number	MFCD03791135
ChemACX	X1343028-9
InChI	InChI=1S/C41H32N6O29S8.8Na/c48-37(44-29-5-1-25(77(53,54)55)15-33(29)81(65,66)67)19-9-20(38(49)45-30-6-2-26(78(56,57)58)16-34(30)82(68,69)70)12-23(11-19)42-41(52)43-24-13-21(39(50)46-31-7-3-27(79(59,60)61)17-35(31)83(71,72)73)10-22(14-24)40(51)47-32-8-4-28(80(62,63)64)18-36(32)84(74,75)76;;;;;;;;/h1-18H,(H,44,48)(H,45,49)(H,46,50)(H,47,51)(H2,42,43,52)(H,53,54,55)(H,56,57,58)(H,59,60,61)(H,62,63,64)(H,65,66,67)(H,68,69,70)(H,71,72,73)(H,74,75,76);;;;;;;;/q;8*+1/p-8
SMILES	c1cc(c(cc1S(=O)(=O)[O-])S(=O)(=O)[O-])NC(=O)c2cc(cc(c2)NC(=O)Nc3cc(cc(c3)C(=O)Nc4ccc(cc4S(=O)(=O)[O-])S(=O)(=O)[O-])C(=O)Nc5ccc(cc5S(=O)(=O)[O-])S(=O)(=O)[O-])C(=O)Nc6ccc(cc6S(=O)(=O)[O-])S(=O)(=O)[O-].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]

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