Rosuvastatin belongs to a class of compounds called statins that is used to reduce plasma cholesterol levels and prevent cardiovascular disease. It competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase, an enzyme that catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis.

Additional Information

Synonyms	(3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid
Product #	R-2421
CAS #	287714-41-4
Chemical Name	(3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid
Formula	C22H28FN3O6S
MW	481.54
Appearance	White to off-white Solid
Purity	98% by HPLC
Solubility	DMSO
Storage Temp	-20°C
Therapeutic Area	Cardiological Disorders
Use	Rosuvastatin belongs to a class of compounds called statins that is used to reduce plasma cholesterol levels and prevent cardiovascular disease

Additional Information

MDL Number	MFCD18783208
ChemACX	X1608533-9
InChI	InChI=1S/C22H28FN3O6S/c1-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32/h5-10,13,16-17,27-28H,11-12H2,1-4H3,(H,29,30)/b10-9+/t16-,17-/m1/s1
SMILES	CC(C)c1c(c(nc(n1)N(C)S(=O)(=O)C)c2ccc(cc2)F)/C=C/[C@H](C[C@H](CC(=O)O)O)O