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Ro 61-8048
品牌:AG Scientific
货号:
规格:5 mg
货期:

CAS:199666-03-0Formula:C17H15N3O6S2MW:421.45Appearance:Off-WhiteSolidPurity:98%byHPLC

商品详情 参考文献 相关资料
Cell-permeable. A high-affinity small molecule inhibitor of KMO (kynurenine 3-monoxygenase or kynurenine 3-hydroxylase)(K = 4.8 nM, IC= 37 nM).

Additional Information

Synonyms3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide
Product #R-2419
CAS #199666-03-0
Chemical Name3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide
FormulaC17H15N3O6S2
MW421.45
AppearanceOff-White Solid
Purity98% by HPLC
SolubilityDMSO (100 mM) or EtOH (10 mM)
Storage Temp-20°C
Therapeutic AreaNeurological Disorders
UseRo 61-8048 is a potent and competitive kynurenine 3-hydroxylase (KMO) inhibitor in Huntington's disease

Additional Information

MDL NumberMFCD11040807
ChemACXX1755810-6
InChIInChI=1S/C17H15N3O6S2/c1-25-15-7-6-13(9-16(15)26-2)28(23,24)19-17-18-14(10-27-17)11-4-3-5-12(8-11)20(21)22/h3-10H,1-2H3,(H,18,19)
SMILESCOc1ccc(cc1OC)S(=O)(=O)Nc2nc(cs2)c3cccc(c3)[N+](=O)[O-]
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