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NSC-23766

品牌：AG Scientific

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规格：1 mg

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CAS:733767-34-5Formula:C24H35N7.3HClMW:530.97Appearance:WhiteSolidPurity:98%

商品详情参考文献相关资料

A cell-permeable, reversible, and selective Rac1 inhibitor; inhibiting Rac1 activation by the Rac-specific guanine nucleotide exchange factors (GEFs) TrioN an Tiam 1 without affecting the closely related GTPases, Cdc42, and RhoA activation. NSC 23766 has been used to investigate the role of Rac1 in such diverse cellular functions as stem cell mobilization, epithelial cell migration, angiogenesis, leukemia cell migration and growth

Additional Information

Synonyms	RAC 1 INHIBITOR
Product #	N-1217
CAS #	733767-34-5
Chemical Name	6-N-[2-[5-(DIETHYLAMINO)PENTAN-2-YLAMINO]-6-METHYLPYRIMIDIN-4-YL]-2-METHYLQUINOLINE-4,6-DIAMINE TRIHYDROCHLORIDE
Formula	C₂₄H₃₅N₇.₃HCl
MW	530.97
Appearance	White Solid
Purity	98%
Solubility	Soluble in water (100mM).
Storage Temp	-20°C
Therapeutic Area	Oncological Disorders
Use	The inhibition of NSC23766 on cell cycle arrest or apoptosis in breast cancer

Additional Information

MDL Number	MFCD08703096
ChemACX	X1579306-5
InChI	InChI=1S/C24H35N7.3ClH/c1-6-31(7-2)12-8-9-16(3)27-24-28-18(5)14-23(30-24)29-19-10-11-22-20(15-19)21(25)13-17(4)26-22;;;/h10-11,13-16H,6-9,12H2,1-5H3,(H2,25,26)(H2,27,28,29,30);3*1H
SMILES	CCN(CC)CCCC(C)Nc1nc(cc(n1)Nc2ccc3c(c2)c(cc(n3)C)N)C.Cl.Cl.Cl

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