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Gilvocarcin V
品牌:AG Scientific
货号:
规格:0.5 mg
货期:

CAS:77879-90-4Formula:C27H26O9MW:494.5Appearance:YellowcrystalsPurity:>95%byHPLC

商品详情 参考文献 相关资料
*Please inquire the availability for this product. Gilvocarcin V is the major analogue of a complex of C-glycoside antitumor actives isolated from a Streptomyces sp.. Gilvocarcin V contains a vinyl group in the 8-position, and is the most potent analogue of the complex. It is thought to act as an inhibitor of the catalytic activity of human topoisomerase II. The metabolite displays potent antibacterial, antifungal, antiviral and antitumor activity. Recent research suggests that the gilvocarcins act as photoactivated cross-linkers of DNA to histones.

Additional Information

SynonymsAnandimycin A, Toromycin, 1072B
Product #G-2519
CAS #77879-90-4
FormulaC27H26O9
MW494.5
AppearanceYellow crystals
Purity>95% by HPLC
SolubilitySoluble in DMSO, DMF (moderately), methanol (moderately), ethanol (moderately), and water (poor)
Melting Point322.54 °C
Storage Temp-20°C
Therapeutic AreaOncological Disorders
UseA metabolite that displays potent antibacterial, antifungal and antiviral activity

Additional Information

MDL NumberMFCD01939442
InChIInChI=1S/C27H26O9/c1-5-12-8-15-19(17(9-12)33-3)14-10-18(34-4)21-16(29)7-6-13(20(21)25(14)36-27(15)32)26-23(31)22(30)24(35-26)11(2)28/h5-11,22-24,26,28-31H,1H2,2-4H3/t11?,22?,23?,24?,26-/m1/s1
SMILESCC(C1C(C([C@H](O1)c2ccc(c3c2c4c(cc3OC)c5c(cc(cc5OC)C=C)c(=O)o4)O)O)O)O
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