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PDGFRTyrosine Kinase Inhibitor II

品牌：AG Scientific

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规格：1 mg

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CAS:249762-74-1Formula:C21H18N2O3MW:346.4Appearance:SolidPurity:97%

商品详情参考文献相关资料

A cell permeable bis(1H-2-indolyl)-1-methanone compound that acts as a highly selective, ATP-competitive and reversible inhibitor of platelet-derived growth factor receptor tyrosine kinase. Also potently inhibits Flt3 activity. Sensitzes 32D cells to radiation-induced apoptosis and inhibits prliferation of TEL-Flt3-transfected BA-F3 cells. May also serce as a prodrug for of the PDGF Receptor Tyrosine Kinase Inhibitor I in cells.

Additional Information

Product #	P-1687
CAS #	249762-74-1
Chemical Name	(5-BUTANOATE-1H-2-INDOLYL)(1H-2-INDOLYL)-METHANONE
Formula	C₂₁H₁₈N₂O₃
MW	346.4
Appearance	Solid
Purity	97%
Solubility	DMSO
Storage Temp	+2°C to +8°C
Use	A cell-permeable isothiourea compound that perturbs MreB function

Additional Information

MDL Number	MFCD06411445
InChI	InChI=1S/C21H18N2O3/c1-2-5-20(24)26-15-8-9-17-14(10-15)12-19(23-17)21(25)18-11-13-6-3-4-7-16(13)22-18/h3-4,6-12,22-23H,2,5H2,1H3
SMILES	CCCC(=O)Oc1ccc2c(c1)cc([nH]2)C(=O)c3cc4ccccc4[nH]3

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