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Hh Signaling Pathway Antagonist

品牌：AG Scientific

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规格：1 mg

货期：

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CAS:330796-24-2Formula:C23H15ClF4N4O2MW:490.84Appearance:Whitetooff-whiteSolidPurity:97%byHPLC

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Cell-permeable. A potent antagonist of the Hedgehog (Hh) signaling pathway (IC= 70 nM).

Synonyms	N-[4-Chloro-3-(trifluoromethyl)phenyl]-N-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl-urea
Product #	H-2354
CAS #	330796-24-2
Chemical Name	N-[4-Chloro-3-(trifluoromethyl)phenyl]-N’-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl-urea
Formula	C₂₃H₁₅ClF₄N₄O₂
MW	490.84
Appearance	White to off-white Solid
Purity	97% by HPLC
Solubility	Soluble in DMSO
Storage Temp	+4°C
Use	It is a potent modulator of Hedgehog (Hh) protein function and a nanomolar hedgehog antagonist

MDL Number	MFCD10567691
ChemACX	X1823651-2
InChI	InChI=1S/C23H15ClF4N4O2/c24-18-10-7-14(11-17(18)23(26,27)28)30-22(34)29-12-20-31-19-4-2-1-3-16(19)21(33)32(20)15-8-5-13(25)6-9-15/h1-11H,12H2,(H2,29,30,34)
SMILES	C1=CC=C2C(=C1)C(=O)N(C(=N2)CNC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)C4=CC=C(C=C4)F

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