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EZSolution SB-431542
品牌:AG Scientific
货号:
规格:1 mg
货期:

CAS:301836-41-9Formula:C22H18N4O3MW:384.39Appearance:LiquidPurity:98%

商品详情 参考文献 相关资料

SB-431542 is a potent and selective inhibitor of TGF-β superfamily type I activin receptor-like kinase (ALK) receptors, specifically ALK4, ALK5 and ALK7. Inhibition of TGF-β signaling is known to induce the de-repression of epithelial fate and thus was hypothesized to benefit the reprogramming process. 

Additional Information

Synonyms4-[4-(1,3-benzodioxol-5-yl)-5-pyridin-2-yl-1H-imidazol-2-yl]benzamide
Product #E-2320
CAS #301836-41-9
Chemical Name4-[4-(1,3-benzodioxol-5-yl)-5-pyridin-2-yl-1H-imidazol-2-yl]benzamide
FormulaC22H18N4O3
MW384.39
AppearanceLiquid
Purity98%
Melting Point315.72 °C
Storage Temp-20°C
Therapeutic AreaOncological Disorders
UseA specific and selective inhibitor of TGF-ß type I ALK receptors and Smad3.It also suppressed the TGF-beta-induced proliferation of osteosarcoma

Additional Information

MDL NumberMFCD05865244
ChemACXX1430393-8
InChIInChI=1S/C22H16N4O3/c23-21(27)13-4-6-14(7-5-13)22-25-19(20(26-22)16-3-1-2-10-24-16)15-8-9-17-18(11-15)29-12-28-17/h1-11H,12H2,(H2,23,27)(H,25,26)
SMILESc1ccnc(c1)c2c(nc([nH]2)c3ccc(cc3)C(=O)N)c4ccc5c(c4)OCO5
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