A potent, cell-permeable, inhibitor of protein kinase C (PKC) that has been shown to selectively inhibit several PKC isozymes (IC =7 nM for PKC and PKC;6 nM for PKC; 10 nM for PKC; 60 nM for PKC). G6983 is reportedly not effective inhibitor of PKC (IC=20M), allowing for use to differentiate PKC from other PKC isozymes.

Additional Information

Product #	G-1249
Formula	C26H26N4O3
MW	442.5
Appearance	Orange Red Solid
Purity	95%
Solubility	DMSO (100 mg/ml)
Melting Point	339.11 °C
Storage Temp	-20°C

Additional Information

MDL Number	MFCD04040031
ChemACX	X1535138-9
InChI	InChI=1S/C26H26N4O3/c1-29(2)11-6-12-30-15-20(18-13-16(33-3)9-10-22(18)30)24-23(25(31)28-26(24)32)19-14-27-21-8-5-4-7-17(19)21/h4-5,7-10,13-15,27H,6,11-12H2,1-3H3,(H,28,31,32)
SMILES	CN(C)CCCn1cc(c2c1ccc(c2)OC)C3=C(C(=O)NC3=O)c4c[nH]c5c4cccc5