血管内皮细胞有维持血管内环境平衡的功能，血管内皮细胞产生、分泌纤维蛋白凝集和分解系统的活化剂和抑制剂。另外它们调控血小板的粘附和聚集。内皮细胞同时释放分子，调控细胞增殖，控制血管壁功能。人脐静脉内皮细胞是应用*普遍的进行体外研究内皮细胞的细胞类型。脐静脉内皮细胞显微镜下形态如同鹅卵石，用vWF/Factor VIII 和 CD-31容易染色,可以摄入乙酰基化低密度脂蛋白。用IL-1或TNF-α预处理后，可选择性地表达E-selectin和VCAM。
Sciencell研究实验室的脐静脉内皮细胞是从人脐带组织分离得到的，原代冻存，冰冻运输。每管细胞密度*过5×10^5/ml。细胞特性经vWF/Factor VIII和CD31 (P-CAM) 免疫荧光鉴定，能够摄取DiI标记乙酰化低密度脂蛋白(DiI-Ac-LDL)。本细胞经检测不含HIV-1、HBV、HCV、支原体、细菌、酵母菌和真菌。如采用ScienCell 实验室特制的培养基，可保证此细胞15倍增增殖。

推荐培养基：内皮细胞培养基(ECM, Cat. #1001)

货号	8000
产地	美国
缩写	HUVEC
规格	5 x 10^5 /1ml
用途	科研
储存	液氮
运输	干冰

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Question:

Greetings! I am the biosafety officer at our institution, and we've had a researcher order primary HUVEC cells from your company. Would you be able to let us know if you test the cultures/isolates for infectious agents or viruses and what agents you test for?

Answers:

Each cell strain tests negative for HIV, HBV and HCV. However, keep in mind that diagnostic tests are not necessarily 100% accurate, therefore, proper precautions must be taken to avoid inadvertent exposure. Always wear gloves and safety glasses when working with these materials. Never mouth pipette. We recommend following the universal procedures for handling products of human origin as the minimum precaution against contamination.