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Anti-Factor VII Antibody

品牌：Antibodies

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规格：100µl

货期：

应用：

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Anti-Factor VII Antibody

商品详情参考文献相关资料

Overview

Name:	Anti-Factor VII Antibody See all Factor VII primary antibodies
Description:	Rabbit polyclonal antibody to Factor VII
Applications:	WB, IHC
Reactivity:	Human, Mouse
Immunogen:	Recombinant protein fragment contain a sequence corresponding to a region within amino acids 209 and 444 of Factor VII
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Purified by antigen-affinity chromatography.
Formulation:	Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
Storage:	Store at -20?C for long term preservation (recommended). Store at 4?C for short term use.

Target

Function:	Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium (By similarity).
Tissue Specificity:	Plasma and liver.
Sequence Similarities:	Belongs to the peptidase S1 family.
Post-Translational Modification:	The vitamin K-dependent, enzymatic carboxylation of some glutamate residues allows the modified protein to bind calcium.
Cellular Location:	Secreted.
Database Links:	Entrez Gene: 2155?Human Entrez Gene: 14068?Mouse Omim: 227500?Human Omim: 613878?Human SwissProt: P08709?Human SwissProt: P70375?Mouse Unigene: 36989?Human Unigene: 4827?Mouse
Synonyms:	Cf7 Antibody Coagulation factor VII Antibody coagulation factor VII (serum prothrombin conversion accelerator) Antibody Eptacog alfa Antibody F7 Antibody F7 deficiency Antibody FA7_HUMAN Antibody Factor VII Antibody Factor VII deficiency Antibody Factor VII heavy chain Antibody Factor VII light chain Antibody FVII Antibody FVII coagulation protein Antibody Hypoproconvertinemia Antibody OTTHUMP00000018733 Antibody OTTHUMP00000018734 Antibody Proconvertin Antibody Serum prothrombin conversion accelerator Antibody SPCA Antibody
Information:	Target information shown above is from the UniProt Consortium.