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Anti-F13A1 Antibody

品牌：Antibodies

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规格：100µl

货期：

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Anti-F13A1 Antibody

商品详情参考文献相关资料

Name:	Anti-F13A1 Antibody See all F13A1 primary antibodies
Description:	Rabbit polyclonal antibody to F13A1
Specificity:	The antibody detects endogenous levels of total F13A1 protein.
Applications:	WB, IHC
Reactivity:	Human
Immunogen:	Fusion protein corresponding to residues near the C terminal of human Coagulation factor XIII, A1 polypeptide
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	0.5mg / ml
Formulation:	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:	Store at -20?C

Function:	Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.
Involvement in Disease:	Factor XIII subunit A deficiency: An autosomal recessive hematologic disorder characterized by a life-long bleeding tendency, impaired wound healing and spontaneous abortion in affected women.
Sequence Similarities:	Belongs to the transglutaminase superfamily. Transglutaminase family.
Post-Translational Modification:	The activation peptide is released by thrombin.
Cellular Location:	Cytoplasm. Secreted. Secreted into the blood plasma. Cytoplasmic in most tissues, but also secreted in the blood plasma.