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Anti-F11R Antibody

品牌：Antibodies

货号：

规格：100µg

货期：

应用：

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Anti-F11R Antibody

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Overview

Name:	Anti-F11R Antibody See all F11R primary antibodies
Description:	Goat polyclonal antibody to F11R.
Applications:	ELISA, WB
Reactivity:	Human
Immunogen:	Synthetic peptide corresponding to Human F11R (C terminal).
Sequence:	C-QPSARSEGEFKQTS
Host:	Goat
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	100 µg at 0.5 mg/ml.
Product Form:	Liquid
Formulation:	Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3 (PubMed:11489913). The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier (By similarity). Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration (PubMed:11812992). Involved in platelet activation (PubMed:10753840).
Tissue Specificity:	Expressed in endothelium, epithelium and leukocytes (at protein level).
Sequence Similarities:	Belongs to the immunoglobulin superfamily.
Post-Translational Modification:	N-glycosylated.
Cellular Location:	Cell junction > Tight junction. Cell membrane. Localized at tight junctions of both epithelial and endothelial cells.
Database Links:	Entrez Gene: 50848 Human Omim: 605721 Human SwissProt: Q9Y624 Human Unigene: 517293 Human
Synonyms:	CD 321 Antibody CD321 Antibody CD321 antigen Antibody ESTM33 Antibody F11 receptor Antibody F11R Antibody JAM Antibody JAM 1 Antibody JAM A Antibody JAM-1 Antibody JAM-A Antibody JAM1 Antibody JAM1_HUMAN Antibody JAMA Antibody JCAM Antibody Jcam1 Antibody Junction adhesion molecule 1 Antibody Junction adhesion molecule, mouse, homolog of Antibody Junctional Adhesion Molecule 1 Antibody Junctional adhesion molecule A Antibody KAT Antibody Ly106 Antibody PAM 1 Antibody PAM-1 Antibody PAM1 Antibody Platelet adhesion molecule Antibody Platelet adhesion molecule 1 Antibody Platelet F11 receptor Antibody PRO301 Antibody UNQ264 Antibody
Information:	Target information shown above is from the UniProt Consortium.