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Anti-ETV4 Antibody

品牌：Antibodies

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规格：50µl

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Anti-ETV4 Antibody

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Name:	Anti-ETV4 Antibody See all ETV4 primary antibodies
Description:	Rabbit polyclonal antibody to ETV4
Specificity:	ETV4 pAb detects endogenous levels of ETV4 protein.
Applications:	WB, IHC, IF
Reactivity:	Human, Mouse, Rat
Immunogen:	Recombinant full length Human ETV4.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Molecular Weight:	~ 54 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form:	1mg/ml in PBS?with?0.1%?Sodium?Azide,?50%?Glycerol.

Function:	Transcriptional activator that binds to the enhancer of the adenovirus E1A gene; the core-binding sequence is 5'[AC]GGA[AT]GT-3'.
Sequence Similarities:	Belongs to the ETS family.
Post-Translational Modification:	Sumoylated; enhanced upon ERK/MAP kinase pathway activation, it positively regulates the transcriptional activator capacity. Sumoylation at Lys-96 probably requires phosphorylation at Ser-101. Transiently polysumoylated and desumoylated by SENP1. Sumoylation is a prerequisite to polyubiquitination which in turn increases proteasomal-mediated degradation. Probably polyubiquitinated by RNF4 and deubiquitinated by USP2.
Cellular Location:	Nucleus.
Database Links:	Entrez Gene: 2118?Human Entrez Gene: 18612?Mouse Entrez Gene: 360635?Rat Omim: 600711?Human SwissProt: P43268?Human SwissProt: P28322?Mouse Unigene: 434059?Human Unigene: 5025?Mouse Unigene: 195602?Rat
Synonyms:	Adenovirus E1A enhancer binding protein Antibody Adenovirus E1A enhancer-binding protein Antibody E1A F Antibody E1A-F Antibody ETS translocation variant 4 Antibody ets variant gene 4 (E1A enhancer binding protein E1AF) Antibody ETV4 Antibody ETV4_HUMAN Antibody Pea3 Antibody PEA3 protein Antibody PEAS3 Antibody Polyomavirus enhancer activator 3 Antibody Polyomavirus enhancer activator 3 homolog Antibody Protein PEA3 Antibody
Information:	Target information shown above is from the UniProt Consortium.