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Anti-ETV1 Antibody

品牌：Antibodies

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规格：50µl

货期：

应用：

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Anti-ETV1 Antibody

商品详情参考文献相关资料

Overview

Name:	Anti-ETV1 Antibody See all ETV1 primary antibodies
Description:	Rabbit polyclonal antibody to ETV1.
Applications:	WB, IHC, IF
Dilutions:	WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:100.
Reactivity:	Human, Mouse, Rat
Immunogen:	Recombinant protein of human ETV1.
Protein Length:	477
Host:	Rabbit
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Affinity purification.
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	Transcriptional activator that binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3'.
Tissue Specificity:	Very highly expressed in brain, highly expressed in testis, lung and heart, moderately in spleen, small intestine, pancreas and colon, weakly in liver, prostate and thymus, very weakly in skeletal muscle, kidney and ovary and not in placenta and peripheral blood leukocytes.
Involvement in Disease:	Ewing sarcoma: A highly malignant, metastatic, primitive small round cell tumor of bone and soft tissue that affects children and adolescents. It belongs to the Ewing sarcoma family of tumors, a group of morphologically heterogeneous neoplasms that share the same cytogenetic features. They are considered neural tumors derived from cells of the neural crest. Ewing sarcoma represents the less differentiated form of the tumors.
Sequence Similarities:	Belongs to the ETS family.
Post-Translational Modification:	Sumoylated.
Cellular Location:	Nucleus.
Database Links:	Entrez Gene: 2115?Human Entrez Gene: 14009?Mouse Entrez Gene: 362733?Rat Omim: 600541?Human SwissProt: P50549?Human SwissProt: P41164?Mouse Unigene: 22634?Human Unigene: 4866?Mouse Unigene: 56219?Rat
Synonyms:	DKFZp781L0674 Antibody ER81 Antibody ER81 protein Antibody ER81, mouse, homolog of Antibody ETS translocation variant 1 Antibody ets variant gene 1 Antibody Ets-related protein 81 Antibody Etsrp81 Antibody ETV 1 Antibody ETV1 Antibody ETV1_HUMAN Antibody MGC104699 Antibody MGC120533 Antibody MGC120534 Antibody
Information:	Target information shown above is from the UniProt Consortium.