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Anti-Endothelin 1 Antibody

品牌：Antibodies

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规格：100µl

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Anti-Endothelin 1 Antibody

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Overview

Name:	Anti-Endothelin 1 Antibody See all Endothelin 1 primary antibodies
Description:	Rabbit polyclonal antibody to Endothelin 1
Applications:	WB, IF
Reactivity:	Human
Immunogen:	Synthetic peptide contain a sequence corresponding to a region within amino acids 141 and 203 of Human EDN1
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Purified by antigen-affinity chromatography.
Formulation:	Supplied in 0.1M Tris-buffered saline with 20% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
Storage:	Store at -20˚C for long term preservation (recommended). Store at 4˚C for short term use.

Target

Function:	Endothelins are endothelium-derived vasoconstrictor peptides.
Tissue Specificity:	Expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.
Involvement in Disease:	Question mark ears, isolated: An auricular abnormality characterized by a cleft between the lobule and the lower part of the helix, sometimes accompanied by a prominent or deficient upper part of the helix, shallow skin dimple on the posterior surface of the ear, or transposition of the ear lobe/antitragus. Auriculocondylar syndrome 3: A craniofacial malformation syndrome characterized by variable mandibular anomalies, including mild to severe micrognathia, temporomandibular joint ankylosis, cleft palate, and a characteristic ear malformation that consists of separation of the lobule from the external ear, giving the appearance of a question mark (question-mark ear). Other frequently described features include prominent cheeks, cupped and posteriorly rotated ears, preauricular tags, and microstomia.
Sequence Similarities:	Belongs to the endothelin/sarafotoxin family.
Cellular Location:	Secreted.
Database Links:	Entrez Gene: 1906 Human Omim: 131240 Human SwissProt: P05305 Human Unigene: 511899 Human Unigene: 713645 Human
Synonyms:	ARCND3 Antibody Big endothelin-1 Antibody EDN1 Antibody EDN1_HUMAN Antibody Endothelin 1 Antibody ET-1 Antibody ET1 Antibody HDLCQ7 Antibody PPET1 Antibody Preproendothelin 1 Antibody Preproendothelin-1 Antibody QME Antibody
Information:	Target information shown above is from the UniProt Consortium.