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Anti-EGF Antibody

品牌：Antibodies

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规格：100µl

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Anti-EGF Antibody

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Overview

Name:	Anti-EGF Antibody See all EGF primary antibodies
Description:	Rabbit polyclonal antibody to EGF
Specificity:	The antibody detects endogenous levels of total EGF protein.
Applications:	WB, IHC
Reactivity:	Human, Mouse
Immunogen:	Fusion protein corresponding to a region derived from internal residues of human epidermal growth factor
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	1mg / ml
Formulation:	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:	Store at -20?C

Target

Function:	EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. Can induce neurite outgrowth in motoneurons of the pond snail Lymnaea stagnalis in vitro (PubMed:10964941).
Tissue Specificity:	Expressed in kidney, salivary gland, cerebrum and prostate.
Involvement in Disease:	Hypomagnesemia 4: A disorder characterized by massive renal hypomagnesemia and normal levels of serum calcium and calcium excretion. Clinical features include seizures, mild-to moderate psychomotor retardation, and brisk tendon reflexes.
Post-Translational Modification:	O-glycosylated with core 1-like and core 2-like glycans. It is uncertain if Ser-954 or Thr-955 is O-glycosylated. The modification here shows glycan heterogeneity: HexHexNAc (major) and Hex2HexNAc2 (minor).
Cellular Location:	Membrane.
Database Links:	Entrez Gene: 1950?Human Entrez Gene: 13645?Mouse Omim: 131530?Human SwissProt: P01133?Human SwissProt: P01132?Mouse Unigene: 419815?Human Unigene: 252481?Mouse
Synonyms:	AI790464 Antibody Beta urogastrone Antibody beta-urogastrone Antibody EGF Antibody EGF_HUMAN Antibody Epidermal growth factor Antibody HOMG4 Antibody OTTHUMP00000219721 Antibody OTTHUMP00000219722 Antibody Pro epidermal growth factor Antibody Pro epidermal growth factor precursor (EGF) Antibody URG Antibody Urogastrone Antibody
Information:	Target information shown above is from the UniProt Consortium.