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Anti-EGF Antibody

品牌：Antibodies

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规格：100µg

货期：

应用：

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Anti-EGF Antibody

商品详情参考文献相关资料

Overview

Name:	Anti-EGF Antibody See all EGF primary antibodies
Description:	Mouse monoclonal (KT57) antibody to EGF.
Applications:	ELISA, WB, sELISA
Reactivity:	Human
Immunogen:	Recombinant human EGF.
Host:	Mouse
Clonality:	Monoclonal
Clone:	KT57
Isotype:	IgG1
Conjugate:	Unconjugated
Purification:	IgG is purified through a Protein A column.
Concentration:	1 mg/ml
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. Can induce neurite outgrowth in motoneurons of the pond snail Lymnaea stagnalis in vitro (PubMed:10964941).
Tissue Specificity:	Expressed in kidney, salivary gland, cerebrum and prostate.
Involvement in Disease:	Hypomagnesemia 4: A disorder characterized by massive renal hypomagnesemia and normal levels of serum calcium and calcium excretion. Clinical features include seizures, mild-to moderate psychomotor retardation, and brisk tendon reflexes.
Post-Translational Modification:	O-glycosylated with core 1-like and core 2-like glycans. It is uncertain if Ser-954 or Thr-955 is O-glycosylated. The modification here shows glycan heterogeneity: HexHexNAc (major) and Hex2HexNAc2 (minor).
Cellular Location:	Membrane.
Database Links:	Entrez Gene: 1950 Human Omim: 131530 Human SwissProt: P01133 Human Unigene: 419815 Human
Synonyms:	AI790464 Antibody Beta urogastrone Antibody beta-urogastrone Antibody EGF Antibody EGF_HUMAN Antibody Epidermal growth factor Antibody HOMG4 Antibody OTTHUMP00000219721 Antibody OTTHUMP00000219722 Antibody Pro epidermal growth factor Antibody Pro epidermal growth factor precursor (EGF) Antibody URG Antibody Urogastrone Antibody
Information:	Target information shown above is from the UniProt Consortium.