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Anti-ECSIT Antibody

品牌：Antibodies

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规格：100µl

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Anti-ECSIT Antibody

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Name:	Anti-ECSIT Antibody See all ECSIT primary antibodies
Description:	Rabbit polyclonal antibody to ECSIT
Applications:	E, WB, IHC
Reactivity:	Human, Mouse
Immunogen:	Raised against a peptide corresponding to 14 amino acids near the C-terminus of human ECSIT.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Ion exchange chromatography purified
Formulation:	Supplied in PBS containing 0.02% sodium azide.
Storage:	Can be stored at -20?C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Function:	Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development.
Tissue Specificity:	Detected in heart, brain, lung, liver, skeletal muscle, kidney and testis. Detected in embryonic mesoderm and epiblast, and in extraembryonic ectoderm.
Sequence Similarities:	Belongs to the ECSIT family.
Cellular Location:	Cytoplasm. Nucleus. Mitochondrion.
Database Links:	Entrez Gene: 51295?Human Entrez Gene: 26940?Mouse Omim: 608388?Human SwissProt: Q9BQ95?Human SwissProt: Q9QZH6?Mouse Unigene: 515146?Human Unigene: 425568?Mouse
Synonyms:	ECSIT Antibody ECSIT homolog Antibody ECSIT protein Antibody ECSIT_HUMAN Antibody Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial Antibody Evolutionarily conserved signaling intermediate in Toll pathways Antibody Likely ortholog of mouse signaling intermediate in Toll pathway evolutionarily conserved Antibody Protein SITPEC Antibody Signaling intermediate in Toll pathway evolutionarily conserved Antibody SITPEC Antibody SITPEC protein Antibody
Information:	Target information shown above is from the UniProt Consortium.