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Anti-ECE2 Antibody

品牌：Antibodies

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规格：100µl

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Anti-ECE2 Antibody

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Name:	Anti-ECE2 Antibody See all ECE2 primary antibodies
Description:	Rabbit polyclonal antibody to ECE2
Specificity:	The antibody detects endogenous levels of total ECE2 protein.
Applications:	IHC
Reactivity:	Human
Immunogen:	Fusion protein corresponding to a region derived from internal residues of human endothelin converting enzyme 2
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	1mg / ml
Formulation:	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:	Store at -20?C

Function:	Converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides. May limit beta-amyloid peptide accumulation in brain. May also have methyltransferase activity.
Tissue Specificity:	Expressed in brain. Strongly down-regulated in inferior parietal lobe from Alzheimer disease patients (at protein level).
Sequence Similarities:	In the N-terminal section; belongs to the methyltransferase superfamily.
Cellular Location:	Golgi apparatus membrane. Cytoplasmic granule membrane.
Database Links:	Entrez Gene: 9718?Human Omim: 610145?Human SwissProt: O60344?Human Unigene: 146161?Human
Synonyms:	ECE 2 Antibody ECE-2 Antibody ECE2 Antibody ECE2_HUMAN Antibody Endothelin converting enzyme 2 Antibody Endothelin-converting enzyme 2 region Antibody Hypothetical protein MGC2408 Antibody KIAA0604 Antibody MGC17664 Antibody MGC78487 Antibody
Information:	Target information shown above is from the UniProt Consortium.