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Anti-DUSP26 Antibody

品牌：Antibodies

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规格：100µl

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应用：

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Anti-DUSP26 Antibody

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Overview

Name:	Anti-DUSP26 Antibody See all DUSP26 primary antibodies
Description:	Rabbit polyclonal antibody to DUSP26
Applications:	WB, IF
Reactivity:	Human
Immunogen:	Synthetic peptide contain a sequence corresponding to a region within amino acids 22 and 87 of DUSP26
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Purified by antigen-affinity chromatography.
Formulation:	Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
Storage:	Store at -20˚C for long term preservation (recommended). Store at 4˚C for short term use.

Target

Function:	Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK).
Tissue Specificity:	Brain. In the brain it is expressed ubiquitously except in the hippocampus. Expressed in embryonal cancers (retinoblastoma, neuroepithilioma and neuroblastoma) and in anaplatic thyroid cancer.
Sequence Similarities:	Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Cellular Location:	Cytoplasm. Nucleus. Golgi apparatus.
Database Links:	Entrez Gene: 78986 Human SwissProt: Q9BV47 Human Unigene: 8719 Human
Synonyms:	DSP-4 Antibody Dual specificity phosphatase 26 Antibody Dual specificity phosphatase 26 (putative) Antibody Dual specificity phosphatase SKRP3 Antibody Dual specificity protein phosphatase 26 Antibody DUS26_HUMAN Antibody DUSP24 Antibody DUSP26 Antibody Hypothetical protein FLJ31142 Antibody LDP 4 Antibody LDP-4 Antibody Low molecular mass dual specificity phosphatase 4 Antibody Low-molecular-mass dual-specificity phosphatase 4 Antibody MAP kinase phosphatase 8 Antibody MGC1136 Antibody MGC2627 Antibody Mitogen activated protein kinase phosphatase 8 Antibody Mitogen-activated protein kinase phosphatase 8 Antibody MKP-8 Antibody MKP8 Antibody NATA1 Antibody NATA1 protein Antibody Novel amplified gene in thyroid anaplastic cancer Antibody SKRP3 Antibody
Information:	Target information shown above is from the UniProt Consortium.