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Anti-DUSP16 Antibody

品牌：Antibodies

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规格：100µg

货期：

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Anti-DUSP16 Antibody

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Name:	Anti-DUSP16 Antibody See all DUSP16 primary antibodies
Description:	Goat polyclonal antibody to DUSP16.
Applications:	ELISA, IHC
Reactivity:	Human
Immunogen:	Synthetic peptide corresponding to Human DUSP16 (N terminal).
Sequence:	AHEMIGTQIVTER-C
Host:	Goat
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	100 μg at 0.5 mg/ml.
Product Form:	Liquid
Formulation:	Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Function:	Dual specificity protein phosphatase involved in the inactivation of MAP kinases. Dephosphorylates MAPK10 bound to ARRB2.
Sequence Similarities:	Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Post-Translational Modification:	Phosphorylated at Ser-446 by MAPK1/ERK2, which prevents its degradation, and thereby stabilizes it and blocks JNK MAPK activity.
Cellular Location:	Cytoplasm. Nucleus. Cytoplasmic vesicle. After dissociation upon AGTR stimulation, re-associates with ARRB2 on endocytic vesicles.
Database Links:	Entrez Gene: 80824?Human Omim: 607175?Human SwissProt: Q9BY84?Human Unigene: 536535?Human
Synonyms:	Dual specificity phosphatase 16 Antibody Dual specificity protein phosphatase 16 Antibody DUS16_HUMAN Antibody DUSP 16 Antibody DUSP16 Antibody KIAA1700 Antibody MAP kinase phosphatase 7 Antibody MAPK phosphatase 7 Antibody Mitogen activated protein kinase phosphatase 7 Antibody Mitogen-activated protein kinase phosphatase 7 Antibody MKP 7 Antibody MKP-7 Antibody MKP7 Antibody
Information:	Target information shown above is from the UniProt Consortium.