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Anti-DSC2 Antibody

品牌：Antibodies

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规格：100µl

货期：

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Anti-DSC2 Antibody

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Name:	Anti-DSC2 Antibody See all DSC2 primary antibodies
Description:	Rabbit polyclonal antibody to DSC2
Specificity:	The antibody detects endogenous levels of total DSC2 protein.
Applications:	IHC
Reactivity:	Human
Immunogen:	Synthetic peptide corresponding to a region derived from internal residues of human desmocollin 2
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	2.3mg / ml
Formulation:	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:	Store at -20?C

Function:	Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms.
Tissue Specificity:	Expressed in epithelia, myocardium and lymph nodes.
Involvement in Disease:	Arrhythmogenic right ventricular dysplasia, familial, 11: A congenital heart disease characterized by infiltration of adipose and fibrous tissue into the right ventricle and loss of myocardial cells, resulting in ventricular and supraventricular arrhythmias.
Cellular Location:	Cell membrane. Cell junction > Desmosome.