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Anti-DPYSL3 Antibody

品牌：Antibodies

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规格：100µl

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Anti-DPYSL3 Antibody

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Overview

Name:	Anti-DPYSL3 Antibody See all DPYSL3 primary antibodies
Description:	Rabbit polyclonal antibody to DPYSL3
Specificity:	The antibody detects endogenous levels of total DPYSL3 protein.
Applications:	WB, IHC
Reactivity:	Human, Mouse
Immunogen:	Fusion protein corresponding to residues near the C terminal of human dihydropyrimidinase-like 3
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	1.3mg / ml
Formulation:	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:	Store at -20?C

Target

Function:	Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration (By similarity).
Tissue Specificity:	Mainly expressed in heart and skeletal muscle. Also strongly expressed in fetal brain and spinal cord.
Sequence Similarities:	Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.
Post-Translational Modification:	Phosphorylation on Ser-522 by DYRK2 promotes subsequent phosphorylation on Thr-509, Thr-514 and Ser-518 by GSK3.
Cellular Location:	Cytoplasm. Cell projection > Growth cone. Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone.
Database Links:	Entrez Gene: 1809?Human Entrez Gene: 22240?Mouse Omim: 601168?Human SwissProt: Q14195?Human SwissProt: Q62188?Mouse Unigene: 519659?Human Unigene: 428551?Mouse Unigene: 8180?Mouse
Synonyms:	Collapsin response mediator protein 4 Antibody Collapsin response mediator protein 4 long Antibody CRMP 4 Antibody CRMP-4 Antibody CRMP4 Antibody Dihydropyrimidinase like 3 Antibody Dihydropyrimidinase related protein 3 Antibody Dihydropyrimidinase-related protein 3 Antibody DPYL3_HUMAN Antibody DPYSL3 Antibody DRP 3 Antibody DRP-3 Antibody DRP3 Antibody LCRMP Antibody TUC4 Antibody ULIP Antibody ULIP 1 Antibody ULIP-1 Antibody ULIP1 Antibody Unc 33 like phosphoprotein Antibody UNc 33 like phosphoprotein 1 Antibody Unc-33-like phosphoprotein 1 Antibody
Information:	Target information shown above is from the UniProt Consortium.