Anti-Dok-6 (G130) Antibody |产品详情|进口试剂采购网

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Anti-Dok-6 (G130) Antibody

品牌：Antibodies

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规格：50µl

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Anti-Dok-6 (G130) Antibody

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Name:	Anti-Dok-6 (G130) Antibody See all Dok6 primary antibodies
Description:	Rabbit polyclonal antibody to Dok-6 (G130)
Specificity:	Dok-6 (G130) pAb detects endogenous levels of Dok-6 protein.
Applications:	WB, IHC, IF
Reactivity:	Human, Mouse, Rat
Immunogen:	Synthetic peptide, corresponding to amino acids 98-149 of Human Dok-6.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Molecular Weight:	~ 43 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Function:	DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK6 promotes Ret-mediated neurite growth. May have a role in brain development and/or maintenance.
Tissue Specificity:	Highly expressed in fetal and ***** brain. Highly expressed in the cerebellum. Weak expression in kidney, spinal cord and testis.
Sequence Similarities:	Belongs to the DOK family. Type B subfamily.
Post-Translational Modification:	On Ret activation, phosphorylated on one or more C-terminal tyrosine residues by an Src family kinase.
Database Links:	Entrez Gene: 220164?Human Entrez Gene: 623279?Mouse Entrez Gene: 498898?Rat Omim: 611402?Human SwissProt: Q6PKX4?Human SwissProt: Q2MHE5?Mouse
Synonyms:	Docking protein 5 Antibody Docking protein 5 like Antibody Docking protein 6 Antibody DOK 6 Antibody DOK5 Antibody DOK5L Antibody DOK6 Antibody Downstream of tyrosine kinase 6 Antibody HsT3226 Antibody MGC20785 Antibody Protein dok 5 Antibody
Information:	Target information shown above is from the UniProt Consortium.