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Anti-Dio-1 (S186) Antibody

品牌：Antibodies

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规格：50µl

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Anti-Dio-1 (S186) Antibody

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Name:	Anti-Dio-1 (S186) Antibody See all Dio-1 primary antibodies
Description:	Rabbit polyclonal antibody to Dio-1 (S186)
Specificity:	Dio-1 (S186) pAb detects endogenous levels of Dio-1 protein.
Applications:	WB, IHC
Reactivity:	Human, Mouse, Rat
Immunogen:	Synthetic peptide, corresponding to amino acids 154-198 of Human Dio-1.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Molecular Weight:	~ 244 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Function:	Putative transcription factor, weakly pro-apoptotic when overexpressed (By similarity). Tumor suppressor. Required for early embryonic stem cell development.
Tissue Specificity:	Ubiquitous.
Cellular Location:	Cytoplasm. Nucleus. Cytoplasm > Cytoskeleton > Spindle. Translocates to the nucleus after pro-apoptotic stimuli (By similarity). Translocates to the mitotic spindle upon loss of interaction with H3K4me3 during early mitosis.
Database Links:	Entrez Gene: 11083?Human Entrez Gene: 23856?Mouse Omim: 604140?Human SwissProt: Q9BTC0?Human SwissProt: Q8C9B9?Mouse Unigene: 15783?Human Unigene: 517172?Human Unigene: 253836?Mouse Unigene: 485484?Mouse
Synonyms:	BYE 1 Antibody BYE1 Antibody C20orf158 Antibody DATF 1 Antibody DATF-1 Antibody DATF1 Antibody Death associated transcription factor 1 Antibody Death inducer obliterator 1 Antibody Death-associated transcription factor 1 Antibody Death-inducer obliterator 1 Antibody DIDO 1 Antibody DIDO 2 Antibody DIDO 3 Antibody DIDO1 Antibody DIDO1_HUMAN Antibody DIDO2 Antibody DIDO3 Antibody DIO 1 Antibody DIO-1 Antibody DIO1 Antibody dJ885L7.8 Antibody DKFZp434P1115 Antibody FLJ11265 Antibody hDido 1 Antibody hDido1 Antibody KIAA0333 Antibody MGC16140 Antibody
Information:	Target information shown above is from the UniProt Consortium.