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Anti-DcR2 Antibody

品牌：Antibodies

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规格：100µl

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Anti-DcR2 Antibody

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Overview

Name:	Anti-DcR2 Antibody See all DcR2 primary antibodies
Description:	Rabbit polyclonal antibody to DcR2
Applications:	E, WB, ICC
Reactivity:	Human, Mouse, Rat
Immunogen:	Raised against a peptide corresponding to amino acids 249 to 263 of human DcR2 precursor.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Affinity chromatography purified via peptide column
Formulation:	Supplied in PBS containing 0.02% sodium azide.
Storage:	Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target

Function:	Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway.
Tissue Specificity:	Widely expressed, in particular in fetal kidney, lung and liver, and in ***** testis and liver. Also expressed in peripheral blood leukocytes, colon and small intestine, ovary, prostate, thymus, spleen, pancreas, kidney, lung, placenta and heart.
Cellular Location:	Membrane.
Database Links:	Entrez Gene: 8793 Human Omim: 603614 Human SwissProt: Q9UBN6 Human Unigene: 213467 Human
Synonyms:	CD 264 Antibody CD264 Antibody CD264 antigen Antibody DcR 2 Antibody DcR2 Antibody Decoy receptor 2 Antibody Decoy with truncated death domain Antibody OTTHUMP00000123528 Antibody TNF receptor related receptor for TRAIL Antibody TNF related apoptosis inducing ligand receptor 4 Antibody TNF-related apoptosis-inducing ligand receptor 4 Antibody TNFRSF 10D Antibody TNFRSF10D Antibody TR10D_HUMAN Antibody TRAIL R4 Antibody TRAIL receptor 4 Antibody TRAIL receptor with a truncated death domain Antibody TRAIL-R4 Antibody TRAILR4 Antibody TRUNDD Antibody Tumor necrosis factor receptor superfamily member 10D Antibody Tumor necrosis factor receptor superfamily member 10d decoy with truncated death domain Antibody Tumor necrosis factor receptor superfamily member 10D precursor Antibody Tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain Antibody
Information:	Target information shown above is from the UniProt Consortium.