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Anti-DBH Antibody

品牌：Antibodies

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规格：100µg

货期：

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Anti-DBH Antibody

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Name:	Anti-DBH Antibody See all DBH primary antibodies
Description:	Goat polyclonal antibody to DBH.
Applications:	ELISA, WB, IHC
Reactivity:	Human
Immunogen:	Synthetic peptide corresponding to Human DBH (internal region).
Sequence:	C-DNHYSPHFQEIR
Host:	Goat
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	100 μg at 0.5 mg/ml.
Product Form:	Liquid
Formulation:	Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Function:	Conversion of dopamine to noradrenaline.
Involvement in Disease:	Dopamine beta-hydroxylase deficiency: Characterized by profound deficits in autonomic and cardiovascular function, but apparently only subtle signs, if any, of central nervous system dysfunction.
Sequence Similarities:	Belongs to the copper type II ascorbate-dependent monooxygenase family.
Post-Translational Modification:	N-glycosylated.
Cellular Location:	Cytoplasmic vesicle > Secretory vesicle lumen. Cytoplasmic vesicle > Secretory vesicle > Chromaffin granule lumen. Secreted.
Database Links:	Entrez Gene: 1621?Human Omim: 609312?Human SwissProt: P09172?Human Unigene: 591890?Human
Synonyms:	dbh Antibody DBM Antibody Dopamine beta Hydroxylase Antibody Dopamine beta monooxygenase Antibody Dopamine beta-hydroxylase (dopamine beta-monooxygenase) Antibody Dopamine beta-monooxygenase Antibody DOPO_HUMAN Antibody OTTHUMP00000022501 Antibody Soluble dopamine beta-hydroxylase Antibody
Information:	Target information shown above is from the UniProt Consortium.