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Anti-DAZ4 Antibody

品牌：Antibodies

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规格：100µl

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Anti-DAZ4 Antibody

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Name:	Anti-DAZ4 Antibody See all DAZ4 primary antibodies
Description:	Rabbit polyclonal antibody to DAZ4
Specificity:	The antibody detects endogenous levels of total DAZ4 protein.
Applications:	IHC
Reactivity:	Human
Immunogen:	Fusion protein corresponding to a region derived from internal residues of human Deleted in azoospermia protein 4
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	1.8mg / ml
Formulation:	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:	Store at -20?C

Function:	RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation.
Tissue Specificity:	Testis-specific. Expression restricted to premeiotic germ cells, particularly in spermatogonia (at protein level).
Involvement in Disease:	Spermatogenic failure Y-linked 2: A disorder resulting in the absence (azoospermia) or reduction (oligozoospermia) of sperm in the semen, leading to male infertility.
Sequence Similarities:	Belongs to the RRM DAZ family.
Cellular Location:	Cytoplasm. Nucleus. Predominantly cytoplasmic. Nuclear at some stages of spermatozoide development. Localizes both to the nuclei and cytoplasm of spermatozoide differentiation. Nuclear in fetal gonocytes and in spermatogonial nuclei. It then relocates to the cytoplasm during male meiosis.
Database Links:	Entrez Gene: 57135?Human Omim: 400003?Human SwissProt: Q86SG3?Human
Synonyms:	DAZ4 Antibody Deleted in azoospermia 4 Antibody Deleted in azoospermia protein 4 Antibody
Information:	Target information shown above is from the UniProt Consortium.