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Anti-DAAM1 Antibody

品牌：Antibodies

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规格：100µl

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Anti-DAAM1 Antibody

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Name:	Anti-DAAM1 Antibody See all DAAM1 primary antibodies
Description:	Rabbit polyclonal antibody to DAAM1
Specificity:	The antibody detects endogenous levels of total DAAM1 protein.
Applications:	WB, IHC
Reactivity:	Human, Mouse
Immunogen:	Synthetic peptide corresponding to a region derived from internal residues of human dishevelled associated activator of morphogenesis 1
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	3.1mg / ml
Formulation:	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:	Store at -20?C

Function:	Binds to disheveled (Dvl) and Rho, and mediates Wnt-induced Dvl-Rho complex formation. May play a role as a scaffolding protein to recruit Rho-GDP and Rho-GEF, thereby enhancing Rho-GTP formation. Can direct nucleation and elongation of new actin filaments. Involved in building functional cilia (PubMed:16630611, PubMed:17482208). Involved in the organization of the subapical actin network in multiciliated epithelial cells (By similarity).
Tissue Specificity:	Expressed in all tissues examined.
Sequence Similarities:	Belongs to the formin homology family.
Cellular Location:	Cytoplasm. Cytoplasm > Cytoskeleton > Cilium basal body. Perinuclear.
Database Links:	Entrez Gene: 23002?Human Entrez Gene: 208846?Mouse Omim: 606626?Human SwissProt: Q9Y4D1?Human SwissProt: Q8BPM0?Mouse Unigene: 654934?Human
Synonyms:	DAAM 1 Antibody DAAM1 Antibody Dishevelled associated activator of morphogenesis 1 Antibody FLJ41657 Antibody KIAA0666 Antibody
Information:	Target information shown above is from the UniProt Consortium.