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Anti-Cytochrome P450 8B1 Antibody

品牌：Antibodies

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规格：50µl

货期：

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Anti-Cytochrome P450 8B1 Antibody

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Name:	Anti-Cytochrome P450 8B1 Antibody See all Cytochrome P450 8B1 primary antibodies
Description:	Rabbit polyclonal antibody to Cytochrome P450 8B1
Specificity:	The antibody detects endogenous levels of total Cytochrome P450 8B1 protein.
Applications:	WB, IHC
Reactivity:	Human
Immunogen:	Synthesized peptide derived from internal of human Cytochrome P450 8B1.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1.0mg / ml
Formulation:	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage:	Store at -20?C

Function:	Involved in bile acid synthesis and is responsible for the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7 alpha, 12 alpha-dihydroxy-4-cholesten-3-one. Responsible for the balance between formation of cholic acid and chenodeoxycholic acid. Has a rather broad substrate specificity including a number of 7-alpha-hydroxylated C27 steroids.
Tissue Specificity:	Liver.
Sequence Similarities:	Belongs to the cytochrome P450 family.
Cellular Location:	Endoplasmic reticulum membrane. Microsome membrane.
Database Links:	Entrez Gene: 1582?Human Omim: 602172?Human SwissProt: Q9UNU6?Human Unigene: 447793?Human Unigene: 722743?Human
Synonyms:	7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase Antibody 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase Antibody CP8B Antibody CP8B1_HUMAN Antibody CYP12 Antibody CYP8B1 Antibody CYPVIIIB1 Antibody Cytochrome P450 8B1 Antibody Cytochrome P450 subfamily VIIIB (sterol 12 alpha hydroxylase) polypeptide 1 Antibody Cytochrome P450, family 8, subfamily B, polypeptide 1 Antibody Sterol 12-alpha-hydroxylase Antibody
Information:	Target information shown above is from the UniProt Consortium.