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Anti-CYP2W1 Antibody

品牌：Antibodies

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规格：100µl

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Anti-CYP2W1 Antibody

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Name:	Anti-CYP2W1 Antibody See all CYP2W1 primary antibodies
Description:	Rabbit polyclonal antibody to CYP2W1
Specificity:	The antibody detects endogenous levels of total CYP2W1 protein.
Applications:	IHC
Reactivity:	Human
Immunogen:	Fusion protein corresponding to residues near the C terminal of human cytochrome P450, family 2, subfamily W, polypeptide 1
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	2.6mg / ml
Formulation:	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:	Store at -20?C

Function:	Seems to have broad catalytic activity towards several chemicals, including polycyclic aromatic hydrocarbon dihydrodiols and aromatic amines (PubMed:16551781, PubMed:24278521). Active also in the metabolism of indoline substrates and is able to activate aflatoxin B1 into cytotoxic products (PubMed:20805301). Furthermore, it seems to be involved in the oxydation of lysophospholipids and fatty acids (PubMed:22591743).
Tissue Specificity:	Very low levels are detected in fetal and ***** tissues. Highly expressed in several tumor samples, in particular colon and adrenal tumors.
Sequence Similarities:	Belongs to the cytochrome P450 family.
Cellular Location:	Endoplasmic reticulum lumen. Cell membrane. About 8% are expressed on the cell surface.
Database Links:	Entrez Gene: 54905?Human Omim: 615967?Human SwissProt: Q8TAV3?Human Unigene: 272795?Human
Synonyms:	CP2W1_HUMAN Antibody CYP2W 1 Antibody CYP2W1 Antibody CYPIIW1 Antibody Cytochrome P450 2W1 Antibody Cytochrome P450, family 2, subfamily W, polypeptide 1 Antibody MGC34287 Antibody
Information:	Target information shown above is from the UniProt Consortium.