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Anti-CYP27A1 Antibody

品牌：Antibodies

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规格：100µl

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Anti-CYP27A1 Antibody

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Overview

Name:	Anti-CYP27A1 Antibody See all CYP27A1 primary antibodies
Description:	Rabbit polyclonal antibody to CYP27A1
Specificity:	The antibody detects endogenous levels of total CYP27A1 protein.
Applications:	WB, IHC
Reactivity:	Human, Mouse
Immunogen:	Fusion protein corresponding to residues near the C terminal of human cytochrome P450, family 27, subfamily A, polypeptide 1
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	1.1mg / ml
Formulation:	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:	Store at -20?C

Target

Function:	Catalyzes the first step in the oxidation of the side chain of sterol intermediates; the 27-hydroxylation of 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol. Has also a vitamin D3-25-hydroxylase activity.
Involvement in Disease:	Cerebrotendinous xanthomatosis: Rare sterol storage disorder characterized clinically by progressive neurologic dysfunction, premature atherosclerosis, and cataracts.
Sequence Similarities:	Belongs to the cytochrome P450 family.
Cellular Location:	Mitochondrion membrane.
Database Links:	Entrez Gene: 1593?Human Entrez Gene: 104086?Mouse Omim: 606530?Human SwissProt: Q02318?Human SwissProt: Q9DBG1?Mouse Unigene: 516700?Human Unigene: 85083?Mouse
Synonyms:	12-alpha-triol 27-hydroxylase Antibody 5-beta-cholestane-3-alpha Antibody 5-beta-cholestane-3-alpha, 7-alpha, 12-alpha-triol 26-hydroxylase Antibody 5-beta-cholestane-3-alpha, 7-alpha, 12-alpha-triol 27-hydroxylase Antibody 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase Antibody 7-alpha Antibody Cholestanetriol 26 monooxygenase Antibody CP27 Antibody CP27A_HUMAN Antibody CTX Antibody CYP Antibody CYP27 Antibody CYP27A1 Antibody Cytochrome P 450C27/25 Antibody Cytochrome P-450C27/25 Antibody Cytochrome P450 27 Antibody Cytochrome P450 27 mitochondrial Antibody Cytochrome P450 family 27 subfamily A member 1 Antibody Cytochrome P450 family 27 subfamily A polypeptide 1 Antibody Cytochrome P450 subfamily XXVIIA (steroid 27-hydroxylase cerebrotendinous xanthomatosis) polypeptide 1 Antibody mitochondrial Antibody Sterol 26 hydroxylase Antibody Sterol 26 hydroxylase mitochondrial Antibody Sterol 26-hydroxylase Antibody Sterol 27 hydroxylase Antibody Sterol 27-hydroxylase Antibody Vitamin D(3) 25 hydroxylase Antibody Vitamin D(3) 25-hydroxylase Antibody
Information:	Target information shown above is from the UniProt Consortium.