Anti-Cyclin L1 (E491) Antibody |产品详情|进口试剂采购网

您好，欢迎来到拜力生物网站！请登录注册

我的订单 | 联系我们 | 在线客服QQ：3012681483 | 客服电话：400-968-7988 | 工作时间：08:30-17:30

主营产品： ELISA试剂盒、抗体、补体血清、兔补体、干扰素、小鼠测温仪、进口试剂、Quidel代理、Swant代理、PBL Assay Science代理

所在位置：首页 > 产品中心 > Antibodies > Antibodies产品

订购信息

上海拜力生物科技公司

Tel:400-968-7988 021-33779008

Anti-Cyclin L1 (E491) Antibody

品牌：Antibodies

货号：

规格：50µl

货期：

立即购买加入购物车

Anti-Cyclin L1 (E491) Antibody

商品详情参考文献相关资料

Name:	Anti-Cyclin L1 (E491) Antibody See all Cyclin L1 primary antibodies
Description:	Rabbit polyclonal antibody to Cyclin L1 (E491)
Specificity:	Cyclin-L1 (E491) pAb detects endogenous levels of Cyclin-L1 protein.
Applications:	WB, IHC
Reactivity:	Human, Mouse, Rat
Immunogen:	Synthetic peptide, corresponding to amino acids 460-518 of Human Cyclin L1.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Molecular Weight:	~ 60 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Function:	Involved in pre-mRNA splicing. Functions in association with cyclin-dependent kinases (CDKs) (PubMed:18216018). Inhibited by the CDK-specific inhibitor CDKN1A/p21 (PubMed:11980906). May play a role in the regulation of RNA polymerase II (pol II). May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC) (PubMed:12414649, PubMed:15700036).
Tissue Specificity:	Widely expressed. Overexpression in primary tumors of head and neck squamous cell carcinomas (HNSCC).
Sequence Similarities:	Belongs to the cyclin family. Cyclin L subfamily.
Cellular Location:	Nucleus speckle. Nucleus > Nucleoplasm. Found in nuclear intrachromatin granules clusters (IGC), also called nuclear speckles, which are storage compartments for nuclear proteins involved in mRNA processing.
Database Links:	Entrez Gene: 57018?Human Entrez Gene: 56706?Mouse Entrez Gene: 114121?Rat Omim: 613384?Human SwissProt: Q9UK58?Human SwissProt: Q52KE7?Mouse SwissProt: Q9R1Q2?Rat Unigene: 4859?Human Unigene: 175612?Mouse Unigene: 12962?Rat
Synonyms:	Ania 6a Antibody CCNL1 Antibody CCNL1_HUMAN Antibody Cyclin L Antibody Cyclin L gamma Antibody Cyclin L1 Antibody Cyclin-L Antibody Cyclin-L1 Antibody
Information:	Target information shown above is from the UniProt Consortium.