Anti-CtBP1 (Phospho-Ser422) Antibody |产品详情|进口试剂采购网

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Anti-CtBP1 (Phospho-Ser422) Antibody

品牌：Antibodies

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规格：50µl

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Anti-CtBP1 (Phospho-Ser422) Antibody

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Name:	Anti-CtBP1 (Phospho-Ser422) Antibody See all CtBP1 primary antibodies
Description:	Rabbit polyclonal antibody to CtBP1 (Phospho-Ser422)
Specificity:	The antibody detects endogenous levels of CtBP1 only when phosphorylated at serine 422.
Applications:	WB, IHC
Dilutions:	Western blotting: 1:500~1:1000Immunohistochemistry: 1:50~1:100
Reactivity:	Human, Mouse, Rat
Immunogen:	Peptide sequence around phosphorylation site of Serine 422(A-P-S(p)-P-G) derived from Human CtBP1.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Concentration:	1.0mg / ml
Formulation:	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage:	Store at -20?C / 1 year

Function:	Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation.
Tissue Specificity:	Expressed in germinal center B-cells.
Sequence Similarities:	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
Post-Translational Modification:	The level of phosphorylation appears to be regulated during the cell cycle. Phosphorylation by HIPK2 on Ser-422 induces proteasomal degradation.
Cellular Location:	Cytoplasm. Nucleus.
Database Links:	Entrez Gene: 1487?Human Entrez Gene: 13016?Mouse Entrez Gene: 29382?Rat Omim: 602618?Human SwissProt: Q13363?Human SwissProt: O88712?Mouse SwissProt: Q9Z2F5?Rat Unigene: 208597?Human Unigene: 594321?Human Unigene: 7286?Mouse Unigene: 3946?Rat
Synonyms:	BARS Antibody brefeldin A- ribosylated substrate Antibody C terminal binding protein 1 Antibody C-terminal-binding protein 1 Antibody CTBP Antibody CtBP1 Antibody CTBP1_HUMAN Antibody MGC104684 Antibody
Information:	Target information shown above is from the UniProt Consortium.