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Anti-CSTB Antibody

品牌：Antibodies

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规格：100µg

货期：

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Anti-CSTB Antibody

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Name:	Anti-CSTB Antibody See all CSTB primary antibodies
Description:	Goat polyclonal antibody to CSTB.
Applications:	ELISA, WB
Reactivity:	Human
Immunogen:	Synthetic peptide corresponding to Human CSTB (C terminal).
Sequence:	C-QTNKAKHDELTYF
Host:	Goat
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	100 µg at 0.5 mg/ml.
Product Form:	Liquid
Formulation:	Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Function:	This is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B.
Involvement in Disease:	Epilepsy, progressive myoclonic 1: An autosomal recessive disorder characterized by severe, stimulus-sensitive myoclonus and tonic-clonic seizures. The onset, occurring between 6 and 13 years of age, is characterized by convulsions. Myoclonus begins 1 to 5 years later. The twitchings occur predominantly in the proximal muscles of the extremities and are bilaterally symmetrical, although asynchronous. At first small, they become late in the clinical course so violent that the victim is thrown to the floor. Mental deterioration and eventually dementia develop.
Sequence Similarities:	Belongs to the cystatin family.
Cellular Location:	Cytoplasm. Nucleus.
Database Links:	Entrez Gene: 1476 Human Omim: 601145 Human SwissProt: P04080 Human Unigene: 695 Human
Synonyms:	CHROW21 Antibody CPI B Antibody CPI-B Antibody CST 6 Antibody CST6 Antibody CSTB Antibody Cystatin B Antibody Cystatin B (stefin B) Antibody Cystatin-B Antibody CYTB Antibody CYTB_HUMAN Antibody EPM1 Antibody EPM1A Antibody Liver thiol proteinase inhibitor Antibody PME Antibody Stefin B Antibody Stefin-B Antibody STF B Antibody STFB Antibody ULD Antibody
Information:	Target information shown above is from the UniProt Consortium.