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Anti-CRMP-2 (Ab-522) Antibody

品牌：Antibodies

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规格：50µl

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Anti-CRMP-2 (Ab-522) Antibody

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Overview

Name:	Anti-CRMP-2 (Ab-522) Antibody See all CRMP-2 primary antibodies
Description:	Rabbit polyclonal antibody to CRMP-2 (Ab-522)
Specificity:	The antibody detects endogenous levels of total DPYSL2 protein.
Applications:	WB
Reactivity:	Human
Immunogen:	Synthesized peptide derived from C-terminal of human DPYSL2.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1.0mg / ml
Formulation:	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage:	Store at -20˚C

Target

Function:	Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis.
Tissue Specificity:	Ubiquitous.
Sequence Similarities:	Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.
Post-Translational Modification:	3F4, a monoclonal antibody which strongly stains neurofibrillary tangles in Alzheimer disease brains, specifically labels DPYSL2 when phosphorylated on Ser-518, Ser-522 and Thr-509.
Cellular Location:	Cytoplasm > Cytosol. Cytoplasm > Cytoskeleton. Membrane. Tightly but non-covalently associated with membranes.
Database Links:	Entrez Gene: 1808 Human Omim: 602463 Human SwissProt: Q16555 Human Unigene: 173381 Human Unigene: 593187 Human
Synonyms:	Collapsin response mediator protein Antibody Collapsin response mediator protein 2 Antibody Collapsin response mediator protein hCRMP 2 Antibody CRAM Antibody CRMP 2 Antibody CRMP-2 Antibody CRMP2 Antibody DHPRP 2 Antibody DHPRP2 Antibody Dihydropyrimidinase 2 Antibody Dihydropyrimidinase like 2 Antibody Dihydropyrimidinase like 2 long form Antibody Dihydropyrimidinase related protein 2 Antibody Dihydropyrimidinase-related protein 2 Antibody DPYL 2 Antibody DPYL2 Antibody DPYL2_HUMAN Antibody DPYSL 2 Antibody Dpysl2 Antibody DRP-2 Antibody DRP2 Antibody Musunc 33 Antibody Musunc33 Antibody N2A3 Antibody TOAD 64 Antibody TOAD64 Antibody ULIP 2 protein Antibody ULIP-2 Antibody Ulip2 Antibody Unc-33-like phosphoprotein 2 Antibody
Information:	Target information shown above is from the UniProt Consortium.