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Anti-Coronin 1B Antibody

品牌：Antibodies

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规格：100µl

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Anti-Coronin 1B Antibody

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Name:	Anti-Coronin 1B Antibody See all Coronin 1B primary antibodies
Description:	Rabbit polyclonal antibody to Coronin 1B
Applications:	WB, IHC
Reactivity:	Human
Immunogen:	Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 183 of Human CORO1B
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Purified by antigen-affinity chromatography.
Formulation:	Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
Storage:	Store at -20?C for long term preservation (recommended). Store at 4?C for short term use.

Function:	Regulates leading edge dynamics and cell motility in fibroblasts. May be involved in cytokinesis and signal transduction (By similarity).
Sequence Similarities:	Belongs to the WD repeat coronin family.
Post-Translational Modification:	Phosphorylation by PKC on Ser-2 regulates the interaction with the Arp2/3 complex and cell motility in fibroblasts. Phosphorylation does not seem to affect subcellular location.
Cellular Location:	Cytoplasm > Cytoskeleton. Localized to the leading edge in fibroblasts, as well as weakly along actin stress fibers.
Database Links:	Entrez Gene: 57175?Human Omim: 609849?Human SwissProt: Q9BR76?Human Unigene: 6191?Human
Synonyms:	COR1B_HUMAN Antibody CORO 1B Antibody CORO1B Antibody Coronin 1B Antibody Coronin 2 Antibody Coronin actin binding protein 1B Antibody Coronin-1B Antibody Coronin-2 Antibody Coronin1B Antibody Coronin2 Antibody DKFZP762I166 Antibody OTTHUMP00000236823 Antibody
Information:	Target information shown above is from the UniProt Consortium.