Anti-Collagen XVII Antibody |产品详情|进口试剂采购网

您好，欢迎来到拜力生物网站！请登录注册

我的订单 | 联系我们 | 在线客服QQ：3012681483 | 客服电话：400-968-7988 | 工作时间：08:30-17:30

主营产品： ELISA试剂盒、抗体、补体血清、兔补体、干扰素、小鼠测温仪、进口试剂、Quidel代理、Swant代理、PBL Assay Science代理

网站首页产品中心代理品牌新闻资讯资源中心关于我们

所在位置：首页 > 产品中心 > Antibodies > Antibodies产品

订购信息

上海拜力生物科技公司

Tel:400-968-7988 021-33779008

Anti-Collagen XVII Antibody

品牌：Antibodies

货号：

规格：100µl

货期：

应用：

咨询客服

立即购买加入购物车

Anti-Collagen XVII Antibody

商品详情参考文献相关资料

Overview

Name:	Anti-Collagen XVII Antibody See all Collagen XVII primary antibodies
Description:	Rabbit monoclonal antibody to Collagen XVII.
Applications:	WB, IHC, IF, IP
Dilutions:	WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, ICC: 1:50 - 1:200, IP: 1:20 - 1:50.
Reactivity:	Human, Mouse, Rat
Immunogen:	Recombinant protein of human COL17A1.
Host:	Rabbit
Clonality:	Monoclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Affinity purification.
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	May play a role in the integrity of hemidesmosome and the attachment of basal keratinocytes to the underlying basement membrane.
Tissue Specificity:	Detected in skin (PubMed:8618013). In the cornea, it is detected in the epithelial basement membrane, the epithelial cells, and at a lower level in stromal cells (at protein level) (PubMed:25676728). Stratified squamous epithelia. Found in hemidesmosomes. Expressed in cornea, oral mucosa, esophagus, intestine, kidney collecting ducts, ureter, bladder, urethra and thymus but is absent in lung, blood vessels, skeletal muscle and nerves.
Involvement in Disease:	Generalized atrophic benign epidermolysis bullosa: A non-lethal, ***** form of junctional epidermolysis bullosa characterized by life-long blistering of the skin, associated with hair and tooth abnormalities. Epithelial recurrent erosion dystrophy: A corneal dystrophy characterized by recurrent episodes of epithelial erosions from childhood, with occasional impairment of vision. Most patients have attacks of redness, photophobia, epiphora, and ocular pain. Exposure to sunlight or draught, dust and smoke and lack of sleep can precipitate attacks.
Post-Translational Modification:	The intracellular/endo domain is disulfide-linked.
Cellular Location:	Cell junction > Hemidesmosome. Membrane. Localized along the plasma membrane of the hemidesmosome.
Database Links:	Entrez Gene: 1308?Human Entrez Gene: 12821?Mouse Entrez Gene: 294027?Rat Omim: 113811?Human SwissProt: Q9UMD9?Human SwissProt: Q07563?Mouse Unigene: 117938?Human Unigene: 1225?Mouse Unigene: 40392?Rat
Synonyms:	180 kDa bullous pemphigoid antigen 2 Antibody Alpha 1 type XVII collagen Antibody BA16H23.2 Antibody BP 180 Antibody BP180 Antibody BPA 2 Antibody BPAG 2 Antibody BPAG2 Antibody Bullous pemphigoid antigen 2 Antibody COL17A1 Antibody Collagen 17 Antibody Collagen alpha 1 XVII chain Antibody Collagen alpha 1(XVII) chain Antibody Collagen alpha1 XVII chain Antibody Collagen type XVII alpha 1 Antibody Collagen XVII Antibody Collagen XVII alpha 1 polypeptide Antibody CollagenXVII Antibody Epidermolysis bullosa junctional localisata variant Antibody FLJ60881 Antibody KIAA0204 Antibody LAD 1 Antibody LAD1 Antibody
Information:	Target information shown above is from the UniProt Consortium.