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Anti-COL5A1 Antibody

品牌：Antibodies

货号：

规格：50µl

货期：

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Anti-COL5A1 Antibody

商品详情参考文献相关资料

Name:	Anti-COL5A1 Antibody See all COL5A1 primary antibodies
Description:	Rabbit polyclonal antibody to COL5A1
Specificity:	COL5A1 pAb detects endogenous levels of COL5A1 protein.
Applications:	WB, IHC
Reactivity:	Human, Mouse
Immunogen:	Recombinant full length Human COL5A1.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Molecular Weight:	~ 180 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Function:	Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin.
Involvement in Disease:	Ehlers-Danlos syndrome, classic type: A connective tissue disorder characterized by hyperextensible skin, atrophic cutaneous scars due to tissue fragility and joint hyperlaxity.
Sequence Similarities:	Belongs to the fibrillar collagen family.
Post-Translational Modification:	Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.
Cellular Location:	Secreted > Extracellular space > Extracellular matrix.