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Anti-CKAP2 Antibody

品牌：Antibodies

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规格：100µl

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Anti-CKAP2 Antibody

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Overview

Name:	Anti-CKAP2 Antibody See all CKAP2 primary antibodies
Description:	Rabbit polyclonal antibody to CKAP2
Specificity:	The antibody detects endogenous levels of total CKAP2 protein.
Applications:	IHC
Reactivity:	Human
Immunogen:	Full length fusion protein
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	2.9mg / ml
Formulation:	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:	Store at -20?C

Target

Function:	Possesses microtubule stabilizing properties. Involved in regulating aneuploidy, cell cycling, and cell death in a p53/TP53-dependent manner (By similarity).
Tissue Specificity:	Abundant in testis, thymus, and in tumor derived cell lines, while barely detectable in liver, prostate, and kidney.
Sequence Similarities:	Belongs to the CKAP2 family.
Cellular Location:	Cytoplasm > Cytoskeleton. Cytoplasm > Cytoskeleton > Spindle. Cytoplasm > Cytoskeleton > Spindle pole. Contrary to the ectopically expressed protein, endogenous CKAP2 does not colocalize with microtubules in G1, S and early G2. At late G2 and prophase after separation of duplicated centrosomes, colocalizes with gamma-tubulin and centrosome-proximal microtubules. From prometaphase through anaphase B, colocalizes with mitotic spindle poles and spindle microtubules. During cytokinesis, absent from midbody microtubules.
Database Links:	Entrez Gene: 26586?Human Omim: 611569?Human SwissProt: Q8WWK9?Human Unigene: 444028?Human Unigene: 521482?Human Unigene: 728722?Human
Synonyms:	AI461656 Antibody AW228814 Antibody CKAP 2 Antibody CKAP2 Antibody CKAP2_HUMAN Antibody CTCL tumor antigen se20 10 Antibody CTCL tumor antigen se20-10 Antibody Cytoskeleton associated protein 2 Antibody Cytoskeleton-associated protein 2 Antibody DKFZp686L1238 Antibody FLJ10749 Antibody LB1 Antibody se20 10 Antibody TMAP Antibody Tumor and microtubule associated protein Antibody Tumor associated microtubule associated protein Antibody Tumor- and microtubule-associated protein Antibody
Information:	Target information shown above is from the UniProt Consortium.