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Anti-CIP29 Antibody

品牌：Antibodies

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规格：100µl

货期：

应用：

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Anti-CIP29 Antibody

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Overview

Name:	Anti-CIP29 Antibody See all CIP29 primary antibodies
Description:	Rabbit polyclonal antibody to CIP29
Applications:	WB, IHC
Reactivity:	Human
Immunogen:	Recombinant protein fragment contain a sequence corresponding to a region within amino acids 4 and 195 of CIP29
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Purified by antigen-affinity chromatography.
Formulation:	Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
Storage:	Store at -20?C for long term preservation (recommended). Store at 4?C for short term use.

Target

Function:	Binds both single-stranded and double-stranded DNA with higher affinity for the single-stranded form. Specifically binds to scaffold/matrix attachment region DNA. Also binds single-stranded RNA. Enhances RNA unwinding activity of DDX39A. May participate in important transcriptional or translational control of cell growth, metabolism and carcinogenesis. Component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production.
Tissue Specificity:	Low expression in spleen, liver, pancreas, testis, thymus, heart, and kidney. Increased levels are seen in hepatocellular carcinoma and pancreatic adenocarcinoma.
Cellular Location:	Nucleus. Nucleus speckle.
Database Links:	Entrez Gene: 84324?Human Omim: 610049?Human SwissProt: P82979?Human Unigene: 505676?Human
Synonyms:	CIP29 Antibody Cytokine induced protein of 29 kDa Antibody Cytokine-induced protein of 29 kDa Antibody HCC 1 Antibody HCC1 Antibody HSPC316 Antibody Nuclear protein Hcc 1 Antibody Nuclear protein Hcc-1 Antibody Proliferation associated cytokine inducible protein CIP29 Antibody Proliferation-associated cytokine-inducible protein CIP29 Antibody SAP domain-containing ribonucleoprotein Antibody SARNP Antibody SARNP_HUMAN Antibody THO1 Antibody
Information:	Target information shown above is from the UniProt Consortium.