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Anti-CHSY1 Antibody

品牌：Antibodies

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规格：50µl

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Anti-CHSY1 Antibody

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Overview

Name:	Anti-CHSY1 Antibody See all CHSY1 primary antibodies
Description:	Rabbit polyclonal antibody to CHSY1
Specificity:	The antibody detects endogenous levels of total CHSY1 protein.
Applications:	WB, IHC
Reactivity:	Human
Immunogen:	Synthesized peptide derived from internal of human CHSY1.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1.0mg / ml
Formulation:	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage:	Store at -20?C

Target

Function:	Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Involved in the negative control of osteogenesis likely through the modulation of NOTCH signaling.
Tissue Specificity:	Ubiquitous, with the highest levels in placenta. Detected at low levels in brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, adrenal gland, mammary gland, stomach, small intestine, lung and peripheral blood leukocytes.
Involvement in Disease:	Temtamy preaxial brachydactyly syndrome: A syndrome characterized by multiple congenital anomalies, mental retardation, sensorineural deafness, talon cusps of upper central incisors, growth retardation, and bilateral symmetric digital anomalies mainly in the form of preaxial brachydactyly and hyperphalangism.
Sequence Similarities:	Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
Cellular Location:	Golgi apparatus > Golgi stack membrane. Secreted.
Database Links:	Entrez Gene: 22856?Human Omim: 608183?Human SwissProt: Q86X52?Human Unigene: 110488?Human
Synonyms:	Carbohydrate synthase 1 Antibody Chondroitin glucuronyltransferase 1 Antibody Chondroitin glucuronyltransferase II Antibody Chondroitin sulfate synthase 1 Antibody Chondroitin synthase 1 Antibody CHSS1_HUMAN Antibody CHSY Antibody ChSy-1 Antibody CHSY1 Antibody CSS1 Antibody Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1 Antibody N acetylgalactosaminyltransferase II Antibody N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1 Antibody N-acetylgalactosaminyltransferase 1 Antibody TPBS Antibody
Information:	Target information shown above is from the UniProt Consortium.