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Anti-CHRM2 Antibody

品牌：Antibodies

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规格：100µg

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应用：

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Anti-CHRM2 Antibody

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Overview

Name:	Anti-CHRM2 Antibody See all CHRM2 primary antibodies
Description:	Goat polyclonal antibody to CHRM2.
Applications:	ELISA, WB
Reactivity:	Mouse
Immunogen:	Synthetic peptide corresponding to Human CHRM2 (internal region).
Sequence:	C-QNGDEKQNIVARK
Host:	Goat
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	100 µg at 0.5 mg/ml.
Product Form:	Liquid
Formulation:	Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol (By similarity).
Sequence Similarities:	Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM2 sub-subfamily.
Post-Translational Modification:	Phosphorylated in response to agonist treatment.
Cellular Location:	Cell membrane. Cell junction > Synapse > Postsynaptic cell membrane. Phosphorylation in response to agonist binding promotes receptor internalization.
Database Links:	Entrez Gene: 243764 Mouse SwissProt: Q9ERZ4 Mouse Unigene: 448632 Mouse
Synonyms:	7TM receptor Antibody Acetylcholine receptor, muscarinic, 2 Antibody AChR Antibody Acm2 Antibody ACM2_HUMAN Antibody Cholinergic receptor muscarinic 2 Antibody Cholinergic receptor, muscarinic 2, cardiac Antibody Cholinergic receptor, muscarinic 2, isoform a Antibody Cholinergic receptor, muscarinic 2a Antibody CHRM 2 Antibody CHRM2 Antibody chrm2a Antibody CM2 Antibody FLJ43243 Antibody HM 2 Antibody HM2 Antibody M2 Antibody M2 muscarinic receptor Antibody M2-mAChR Antibody MGC120006 Antibody MGC120007 Antibody Muscarinic Acetylcholine Receptor 2 Antibody Muscarinic acetylcholine receptor M2 Antibody Muscarinic M2 receptor Antibody
Information:	Target information shown above is from the UniProt Consortium.