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Anti-CENPM Antibody

品牌：Antibodies

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规格：100µl

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Anti-CENPM Antibody

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Name:	Anti-CENPM Antibody See all CENPM primary antibodies
Description:	Rabbit polyclonal antibody to CENPM
Specificity:	The antibody detects endogenous levels of total CENPM protein.
Applications:	IHC
Dilutions:	Immunohistochemistry: 1:100-1:200
Reactivity:	Human
Immunogen:	Full length fusion protein
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	1.6mg / ml
Formulation:	Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Storage:	Store at -20?C

Function:	Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres.
Tissue Specificity:	Isoform 3 is highly expressed in spleen, and intermediately in heart, prostate and ovary. Isoform 3 is highly expressed in resting CD19 B-cells and B-lineage chronic lymphocytic leukemia (B-CLL) cells and weakly expressed in activated B-cells. Isoform 1 is selectively expressed in activated CD19 cells and weakly in resting CD19 B-cells.
Cellular Location:	Nucleus. Cytoplasm. Chromosome > Centromere > Kinetochore. Nuclear in non-confluent cells and cytoplasmic in confluent or dividing cells (By similarity). Localizes in the kinetochore domain of centromeres.
Synonyms:	bK250D10.2 Antibody C22orf18 Antibody CENP M Antibody CENPM Antibody Centromere protein M Antibody ICEN 39 Antibody ICEN39 Antibody Interphase centromere complex protein 39 Antibody MGC861 Antibody OTTHUMP00000028741 Antibody PANE 1 Antibody PANE1 Antibody Proliferation associated nuclear element 1 Antibody Proliferation associated nuclear element protein 1 Antibody
Information:	Target information shown above is from the UniProt Consortium.