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Anti-CDX2 Antibody

品牌：Antibodies

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规格：100µl

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Anti-CDX2 Antibody

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Overview

Name:	Anti-CDX2 Antibody See all CDX2 primary antibodies
Description:	Rabbit polyclonal antibody to CDX2
Applications:	E, WB, IHC
Reactivity:	Human, Mouse, Rat
Immunogen:	Raised against a 16 amino acid peptide near the carboxy terminus of human CDX2.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Affinity chromatography purified via peptide column
Formulation:	Supplied in PBS containing 0.02% sodium azide.
Storage:	Can be stored at -20?C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target

Function:	Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine.
Tissue Specificity:	Intestine; expressed specifically in gut epithelium where it is not restricted to a particular cell lineage. Abundant expression is seen in the proximal colon with slightly lower levels in distal colon. Expression in the proximal colon is not restricted either to a particular cell lineage or stage of differentiation while in the distal colon it is more abundant in the differentiated cells towards the top of the crypt.
Sequence Similarities:	Belongs to the Caudal homeobox family.
Post-Translational Modification:	Phosphorylation of Ser-60 mediates the transactivation capacity.
Cellular Location:	Nucleus.
Database Links:	Entrez Gene: 1045?Human Entrez Gene: 12591?Mouse Entrez Gene: 66019?Rat Omim: 600297?Human SwissProt: Q99626?Human SwissProt: P43241?Mouse Unigene: 174249?Human Unigene: 20358?Mouse Unigene: 64495?Rat
Synonyms:	Caudal type homeo box 2 Antibody Caudal type homeo box transcription factor 2 Antibody Caudal type homeobox 2 Antibody Caudal type homeobox protein 2 Antibody Caudal type homeobox transcription factor 2 Antibody Caudal-type homeobox protein 2 Antibody CDX 2 Antibody CDX 3 Antibody CDX-3 Antibody CDX2 Antibody CDX2/AS Antibody CDX2_HUMAN Antibody CDX3 Antibody Homeobox protein CDX 2 Antibody Homeobox protein CDX-2 Antibody
Information:	Target information shown above is from the UniProt Consortium.