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Anti-CDK11A / CDK11B Antibody

品牌：Antibodies

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规格：100µl

货期：

应用：

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Anti-CDK11A / CDK11B Antibody

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Overview

Name:	Anti-CDK11A / CDK11B Antibody See all CDK11A primary antibodies
Description:	Rabbit polyclonal antibody to CDK11A / CDK11B
Specificity:	The antibody detects endogenous levels of total CDK11A / CDK11B protein.
Applications:	WB, IHC
Reactivity:	Human, Mouse
Immunogen:	Synthetic peptide corresponding to residues near the N terminal of human cyclin-dependent kinase 11A / B
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	2.2mg / ml
Formulation:	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:	Store at -20?C

Target

Function:	Plays multiple roles in cell cycle progression, cytokinesis and apoptosis. Involved in pre-mRNA splicing in a kinase activity-dependent manner. Isoform 7 may act as a negative regulator of normal cell cycle progression.
Tissue Specificity:	Expressed ubiquitously. Some evidence of isoform-specific tissue distribution.
Sequence Similarities:	Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Post-Translational Modification:	During FAS- or TNF-induced apoptosis, isoform SV9 is cleaved by caspases to produce p110C, a fragment that contains the C-terminal kinase domain.
Cellular Location:	Cytoplasm. Nucleus.
Database Links:	Entrez Gene: 728642?Human Entrez Gene: 12537?Mouse Omim: 116951?Human SwissProt: Q9UQ88?Human SwissProt: P24788?Mouse Unigene: 651228?Human Unigene: 709182?Human Unigene: 709182?Mouse
Synonyms:	CD11A_HUMAN Antibody CDC2L2 Antibody CDC2L3 Antibody CDK11 Antibody CDK11 / CDC2L2 Antibody CDK11 p110 Antibody CDK11 p46 Antibody CDK11 p58 Antibody CDK11A Antibody Cell division cycle 2 like 2 (PITSLRE proteins) Antibody Cell division cycle 2-like protein kinase 2 Antibody Cell division protein kinase 11A Antibody Cyclin-dependent kinase 11A Antibody Galactosyltransferase-associated protein kinase p58/GTA Antibody p58GTA Antibody PITSLRE Antibody PITSLRE B Antibody PITSLRE protein kinase beta Antibody PITSLRE serine/threonine-protein kinase CDC2L2 Antibody PITSLREB Antibody
Information:	Target information shown above is from the UniProt Consortium.