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Anti-CDC23 Antibody

品牌：Antibodies

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规格：100µl

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Anti-CDC23 Antibody

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Name:	Anti-CDC23 Antibody See all CDC23 primary antibodies
Description:	Rabbit polyclonal antibody to CDC23
Specificity:	The antibody detects endogenous levels of total CDC23 protein.
Applications:	WB, IHC
Reactivity:	Human, Mouse
Immunogen:	Synthetic peptide corresponding to a region derived from internal residues of human cell division cycle 23
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	2.9mg / ml
Formulation:	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:	Store at -20?C

Function:	Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Sequence Similarities:	Belongs to the APC8/CDC23 family.
Post-Translational Modification:	Phosphorylated. Phosphorylation on Thr-562 occurs specifically during mitosis.
Database Links:	Entrez Gene: 8697?Human Entrez Gene: 52563?Mouse Omim: 603462?Human SwissProt: Q9UJX2?Human SwissProt: Q8BGZ4?Mouse Unigene: 73625?Human Unigene: 196638?Mouse
Synonyms:	ANAPC8 Antibody Anaphase promoting complex subunit 8 Antibody Anaphase-promoting complex subunit 8 Antibody Apc 8 Antibody APC8 Antibody Cdc 23 Antibody Cdc23 Antibody CDC23_HUMAN Antibody cell division cycle 23 Antibody Cell division cycle 23 homolog Antibody Cell division cycle protein 23 Antibody Cell division cycle protein 23 homolog Antibody Cut23 Antibody Cyclosome subunit 8 Antibody
Information:	Target information shown above is from the UniProt Consortium.