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Anti-CD74 Antibody

品牌：Antibodies

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规格：100µl

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应用：

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Anti-CD74 Antibody

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Overview

Name:	Anti-CD74 Antibody See all CD74 primary antibodies
Description:	Rabbit polyclonal antibody to CD74
Applications:	WB, IHC
Reactivity:	Human
Immunogen:	Synthetic peptide contain a sequence corresponding to a region within amino acids 1 and 28 of CD74
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Purified by antigen-affinity chromatography.
Formulation:	Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
Storage:	Store at -20?C for long term preservation (recommended). Store at 4?C for short term use.

Target

Function:	Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.
Post-Translational Modification:	N- and O-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans.
Cellular Location:	Cell membrane. Endoplasmic reticulum membrane. Golgi apparatus > trans-Golgi network. Endosome. Lysosome. Transits through a number of intracellular compartments in the endocytic pathway. It can either undergo proteolysis or reach the cell membrane.
Database Links:	Entrez Gene: 972?Human Omim: 142790?Human SwissProt: P04233?Human Unigene: 436568?Human
Synonyms:	CD 74 Antibody CD74 Antibody CD74 antigen Antibody CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) Antibody CD74 molecule Antibody CD74 molecule, major histocompatibility complex, class II invariant chain Antibody CLIP Antibody DHLAG Antibody Gamma chain of class II antigens Antibody HG2A_HUMAN Antibody HLA class II histocompatibility antigen gamma chain Antibody HLA DR antigens associated invariant chain Antibody HLA DR gamma Antibody HLA-DR antigens-associated invariant chain Antibody HLA-DR-gamma Antibody HLADG Antibody HLADR antigens associated invariant chain Antibody Ia antigen associated invariant chain Antibody Ia antigen-associated invariant chain Antibody Ia associated invariant chain Antibody Ia gamma Antibody Ii Antibody Invariant polypeptide of major histocompatibility complex class II antigen associated Antibody la-gamma Antibody Major histocompatibility complex class II invariant chain Antibody MHC HLA DR gamma chain Antibody MHC HLA-DR gamma chain Antibody p33 Antibody p35 Antibody Protein 41 Antibody
Information:	Target information shown above is from the UniProt Consortium.