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Anti-CD57 (V35) Antibody

品牌：Antibodies

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规格：50µl

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Anti-CD57 (V35) Antibody

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Overview

Name:	Anti-CD57 (V35) Antibody See all CD57 primary antibodies
Description:	Rabbit polyclonal antibody to CD57 (V35)
Specificity:	CD57 (V35) pAb detects endogenous levels of CD57 protein.
Applications:	WB, IHC
Reactivity:	Human, Mouse, Rat
Immunogen:	Synthetic peptide, corresponding to amino acids 3-50 of Human CD57.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Molecular Weight:	~ 38 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Target

Function:	Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group.
Tissue Specificity:	Mainly expressed in the brain.
Sequence Similarities:	Belongs to the glycosyltransferase 43 family.
Post-Translational Modification:	The soluble form derives from the membrane form by proteolytic processing.
Cellular Location:	Golgi apparatus membrane. Secreted.
Database Links:	Entrez Gene: 27087?Human Entrez Gene: 76898?Mouse Entrez Gene: 117108?Rat Omim: 151290?Human SwissProt: Q9P2W7?Human SwissProt: Q9CW73?Mouse SwissProt: O35789?Rat Unigene: 381050?Human Unigene: 218788?Mouse Unigene: 88274?Rat
Synonyms:	3-glucuronyltransferase Antibody 3-glucuronyltransferase 1 Antibody B3GA1_HUMAN Antibody B3gat1 Antibody Beta 1 3 glucuronyltransferase 1 Antibody Beta-1 Antibody Beta-1,3-glucuronyltransferase 1 Antibody CD 57 Antibody CD57 Antibody CD57 antigen Antibody Galactosylgalactosylxylosylprotein 3 beta glucuronosyltransferase 1 Antibody Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 Antibody GlcAT P Antibody GlcAT-P Antibody GLCATP Antibody GlcUAT P Antibody GlcUAT-P Antibody GlcUATP Antibody Glucuronosyltransferase P Antibody HNK 1 Antibody HNK1 Antibody LEU 7 Antibody LEU7 Antibody LEU7 antigen Antibody NK 1 Antibody NK1 Antibody UDP GlcUA glycoprotein beta 1 3 glucuronyltransferase Antibody UDP-GlcUA:glycoprotein beta-1 Antibody
Information:	Target information shown above is from the UniProt Consortium.